The current state of the art and future trends in RAS-targeted cancer therapies | Nature Reviews Clinical Oncology
Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics | Scientific Reports
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | bioRxiv
Integrated RAS signaling defined by parallel NMR detection of effectors and regulators | Nature Chemical Biology
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
The Ras switch in structural and historical perspective
JPM | Free Full-Text | Targeting KRAS in Pancreatic Cancer
Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms
BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions | eLife
Modeling the Role of G12V and G13V Ras Mutations in the Ras-GAP-Catalyzed Hydrolysis Reaction of Guanosine Triphosphate | Biochemistry
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling | Journal of Medicinal Chemistry
The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants - Pálfy - Chemistry – A European Journal - Wiley Online Library
RCSB PDB - 1U8Y: CRystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Simulating Ras: 30 years of progress - NCI
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain: IMPLICATIONS OF AN ACTIVATION MECHANISM IN Ras EFFECTOR SPECIFICITY AND SIGNAL DISTRIBUTION - ScienceDirect
Simulating Ras: 30 years of progress - NCI
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
RAS(ON) Inhibitors | Revolution Medicines
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange | PNAS
Cancers | Free Full-Text | Cutting the Brakes on Ras—Cytoplasmic GAPs as Targets of Inactivation in Cancer
Potential for Next Generation RAS Inhibitors in Adult and Pediatric Cancers
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators - ScienceDirect
The Ras switch in structural and historical perspective
Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements - ScienceDirect
